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Chemical and Biological Data Management System
 

The client is one of the world's fastest growing pharmaceutical companies with a massive workforce of 70,000 people throughout the world that discovers, develops, manufactures and markets branded prescription drugs and human vaccines to protect and improve the health of patients around the world. The Company's core business includes its activities in prescription drugs and human vaccines.

Challenges
  • The client needed a fully integrated Chemical and biological data management system to automate R&D processes.
  • The client accepted Activity-Base, a web based third-party application for robust automation and data management to facilitate fast, accurate experimentation and decision making requirements.
  • Radiant's challenge was to efficiently manage and support the application.
  • The client had a TLC (Target, Lead and Candidate) application running, which also required training and support.

Solution & Approach

Activity-Base is a suite of advanced discovery experiment management applications that enable scientists to capture, manage and use all of the data fuelling the drug discovery process, from structure registration, to screening, to dose response, to behavioral studies. Our role was to provide end user application support (data processing, calculation, analysis, template creation, custom scripting and account creation and maintenance), detailed training and troubleshooting for all aspects of Activity-Base. We also identified existing database issues, collaborated with members of a global team to create and implement final problem solutions using the Activity Base Client, PL/SQL and Visual Basic development tools. We were also a point of contact to the third party vendors for consultancy requests and problem diagnostics and solution implementation.

We also supported the TLC Application by using detailed system architecture knowledge to build project and assay query reports, trained users on all aspects of using the TLC query application (Internal Application). Our role also involved generating consolidated reports of biological and chemical research data for project teams and scientists to generate key research project decisions for movement from early stage drug discovery to late stage pre-clinical research.

Sophisticated technology used across multiple layers along with the approach is mentioned as under.

ASP.NET The application User Interface layer is built-on ASP.NET framework
Middleware Servers The middleware server is a distributed, peer-to-peer software component server
Integration Services The Integration Service provides out-of-the-box enterprise-class scalability options
DW & BI - Pre-clinical Areas Radiant solution for Pre-clinical Activities is a highly customizable and easy to use web based data warehousing
DW & BI - Clinical Areas Radiant has architected and implemented with many customers across the globe
 
 
Architecture View
 
 
Figure 5. Architecture View
 
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